B.Pharma Important Question
BP-301T,
Pharmaceutical Organic Chemistry-II,
III Sem, RGPV, B.Pharmacy
UNIT 1 – Benzene and Its Derivatives
Q.1 Give an account on the Friedel crafts alkylation and Friedel crafts acylation reaction with mechanism. (RGPV Dec 2023)
Q.2 Explain the effect of electron withdrawing groups on electrophilic aromatic substitution reaction in benzene. (RGPV Dec 2023)
Q.3 Discuss aromaticity and resonance in benzene. (RGPV Dec 2023)
Q.4 Explain aromatic electrophilic substitution reactions in Benzene with respect to halogenations and Friedel craft acylation with mechanism. (RGPV June 2020)
Q.5 Explain aromaticity and resonance in benzene. Write mechanism and uses of Friedel craft alkylation and Friedel craft acylation. (RGPV Nov 2019)
Q.6 Discuss the effect of substituent on reactivity and orientation of monosubstituted benzene towards electrophilic aromatic substitution. (RGPV Nov 2019)
UNIT 2 – Phenols, Aromatic Amines & Acids
Q.1 Give synthesis and reactions of Phenols. Discuss effect of substituents on acidity of phenols. (RGPV Dec 2023)
Q.2 Give synthesis and reactions of benzoic acid. Explain effect of substituents on acidity of aromatic acids. (RGPV Dec 2023)
Q.3 Explain synthesis, reactions and synthetic uses of aryl diazonium salts. (RGPV Dec 2023)
Q.4 Give synthesis and reactions of Phenols. Discuss effect of substituents on acidity of phenols. (RGPV June 2020)
Q.5 Define aromatic amines and give resonance structure of aniline. Explain basicity of aromatic amines and effect of substituent. (RGPV June 2020)
Q.6 Give synthesis and reactions of benzoic acid. Explain effect of substituents on acidity of Aromatic acids. (RGPV June 2020)
Q.7 Describe the acidity and effect of substituent on acidity of phenols. Write general methods of preparation of phenols. (RGPV Nov 2019)
UNIT 3 – Fats and Oils
Q.1 Discuss principle involved and significance in determination of Saponification value of fats and oils. (RGPV Dec 2023)
Q.2 Write a note on the types of rancidity and the methods for prevention of rancidity. (RGPV Dec 2023)
Q.3 Explain in detail about the determination of Ester value of fats and oils. (RGPV Dec 2023)
Q.4 Explain the principle involved in determination of saponification, Reichert Meissl and Acid value of a fat/oil. (RGPV June 2020)
Q.5 How Saponification value, Ester value and Iodine value calculated? Give significance of Reichert Meissl (RM) value. (RGPV Nov 2019)
UNIT 4 – Polynuclear Hydrocarbons
Q.1 Discuss synthesis, reactions and uses of Triphenylamine. (RGPV Dec 2023)
Q.2 Give structures, synthesis, reactions and uses of Naphthalene. (RGPV Dec 2023)
Q.3 Write synthesis, reactions, structure and medicinal uses of Diphenylamine. (RGPV Dec 2023)
Q.4 Give structures, synthesis, reactions and uses of Naphthalene and Anthracene. (RGPV June 2020)
Q.5 Give synthesis, reactions and uses of naphthalene and anthracene. (RGPV Nov 2019)
UNIT 5 – Cyclo Alkalis
Q.1 Discuss Coulson and Moffitt’s modification. Write reactions of cyclopropane and cyclobutane. (RGPV Dec 2023)
Q.2 Explain Sachse-Mohr theory of stability of cycloalkanes and give its limitations. (RGPV Dec 2023)
Q.3 Explain Baeyer strain theory of stability of Cycloalkanes and give its limitations. Write reactions of Cyclobutane. (RGPV June 2020)
Q.4 Give reactions of cyclopropane and cyclobutane, also explain stability of cycloalkanes on the basis of Baeyer’s strain theory. (RGPV Nov 2019)
Extra Questions
Q.1 Write short notes on any two: (RGPV Dec 2023)
a) Structure and uses of DDT, BHC and Chloramine
b) Structure and uses of cresols and naphthols
c) Fatty acids reactions
d) Baeyer’s strain theory
Q.2 Write short note on any three of the following. (RGPV June 2020)
a) Structure and uses of DDT, BHC and Chloramine
b) Sachse-Mohr theory of stability of cycloalkanes
c) Preparation and reactions of Triphenylmethane
d) Fatty acids reactions
Q.3 Write notes on any three of the following: (RGPV Nov 2019)
a) Sachse Mohr’s theory
b) Huckel’s Rule
c) Diazotization Reaction
d) Reactions of fatty acids
Q.4 Write short note on any three of the following: (RGPV Nov 2019)
a ) Structure and uses of DDT, Saccharin and BHC.
b) Qualitative tests, structure and uses of Cresols and Naphthols.
c) Aromatic acids.
d) Phenanthrene and Triphenylmethane.
— Best of Luck for Exam —
