B.Pharma Important Question
BP-401T,
Pharmaceutical Organic Chemistry-III,
IV Sem, RGPV, B.Pharmacy
UNIT 1 – Stereo Isomerism
Q.1 What is the Optical Activity? Give the stereoisomers of tartaric acid. (RGPV June 2024)
Q.2 What is Racemic modification? Discuss the method of resolution of racemic modification. (RGPV June 2024)
Q.3 What are diastereomers? Explain Meso compounds. (RGPV June 2024)
Q.4 What is Racemic modification? Describe the procedure for resolving racemic modification. (RGPV Nov 2023)
Q.5 What are relative and absolute configurations? Describe the procedures for figuring out R and S configuration. (RGPV Nov 2023)
Q.6 What are symmetric and asymmetric molecules? Explain asymmetric synthesis. (RGPV Nov 2023)
Q.7 Discuss in brief elements of symmetry. (RGPV June 2023)
Q.8 Discuss stereo specific and stereoselective synthesis with example. (RGPV June 2023)
UNIT 2 – Geometrical Isomerism
Q.1 Discuss conformational isomers in Ethane. (RGPV June 2024)
Q.2 Describe the stereoselective reaction with suitable example. (RGPV June 2024)
Q.3 Discuss the various conformational isomers of cyclohexane. (RGPV June 2024)
Q.4 Give the conformational isomers of Ethane. (RGPV Nov 2023)
Q.5 Write a note on E & Z and Syn & Anti systems of nomenclature. (RGPV Nov 2023)
Q.6 Explain the stereochemistry of Biphenyl and the conditions required for optical activity. (RGPV Nov 2023)
Q.7 What is Conformational analysis? Define relative configuration and absolute configuration. (RGPV June 2023)
Q.8 Discuss briefly with example Atropisomerism. (RGPV June 2023)
UNIT 3 – Heterocyclic Compounds
Q.1 What are heterocyclic compounds and how are they classified. (RGPV June 2024)
Q.2 Write a note on aromaticity and reactivity of Thiophene. (RGPV June 2024)
Q.3 Describe the aromaticity and chemical reactivity of furan. (RGPV Nov 2023)
Q.4 Write the structure and medicinal uses of the Pyrrole derivative. Discuss Paal-Knorr Synthesis of Pyrrole. (RGPV Nov 2023)
Q.5 Explain the relative aromaticity and reactivity of Thiophene in contrast to Furan and Pyrrole. (RGPV Nov 2023)
Q.6 Write the structure and medicinal uses of the drug containing the thiophene nucleus. (RGPV Nov 2023)
Q.7 Define and classify Heterocyclic compounds with example. (RGPV June 2023)
Q.8 Comment on synthesis and chemical properties of Pyrrole. (RGPV June 2023)
UNIT 4 – Synthesis, Reaction & Medicinal Uses of Compound
Q.1 Write the synthesis and reactions of Furan. (RGPV June 2024)
Q.2 List the biological compound containing purine ring and its pharmaceutical importance. (RGPV June 2024)
Q.3 Illustrate the Synthesis, reactions, and medicinal uses of Quinoline and Thiazole. (RGPV June 2024)
Q.4 Discuss the basicity of Pyridine. (RGPV June 2024)
Q.5 What do you understand by heterocyclic compound? Give the preparation, properties and pharmaceutical importance of quinoline. (RGPV Nov 2023)
Q.6 Give important properties of pyridine and discuss its chemistry. (RGPV Nov 2023)
Q.7 Write a note on: (RGPV Nov 2023)
a) Fischer-Indole synthesis
b) Lithium Aluminium hydride
Q.8 Describe the preparation, properties and pharmaceutical importance of Indole. (RGPV June 2023)
Q.9 Describe the preparation, properties and pharmaceutical importance of Pyrazole. (RGPV June 2023)
Q.10 Give the methods of synthesis and chemical properties of Quinoline. (RGPV June 2023)
Q.11 Discuss the synthesis and chemical properties of Purine. (RGPV June 2023)
Q.12 Discuss the preparation and Chemical properties of Azepines. (RGPV June 2023)
Q.13 Discuss the synthesis and chemical properties of Pyrimidine. (RGPV June 2023)
UNIT 5 – Reaction of Synthetic Importance
Q.1 Write Wolff-Kishner reduction reaction. (RGPV June 2024)
Q.2 Write the Dakin reaction and its synthetic applications. (RGPV June 2024)
Q.3 Enumerate the synthetic application of Claisen-Schmidt condensation. (RGPV June 2024)
Q.4 Write the Oppenauer-oxidation reaction and its synthetic importance. (RGPV Nov 2023)
Q.5 Explain the mechanism involved in Beckmann rearrangement and its synthetic importance. (RGPV Nov 2023)
Q.6 Explain the reaction with mechanism (RGPV June 2023)
i) Wolff Kishner reduction
ii) Dakin reaction
Q.7 What is oppenaur oxidation? Illustrate its utility in organic synthesis. (RGPV June 2023)
Q.8 Describe Birch reduction reaction with mechanism. (RGPV June 2023)
Q.9 Give the mechanism involved in Claisen-Schmidt condensation. (RGPV June 2023)
— Best of Luck for Exam —
